To dream big snakes in the road might can have a lot of significant meanings. Most of them are negative, but just because it is so, it does not mean that it must happen. So, big snakes in the road dream can mean:
May a swarm of frothing rats find your kidneys suddenly delectable. You friendless offspring of a motherless simpleton. You friendless, hirsute, bad excuse for shit. You crusty, earwax for brains.

Also, dreaming of big snakes in the road can symbolize:
May the hosts of Hades viciously sneeze on your best rug. You bloated, funky, grimy, rancid, damp dingo zits for brains. May a putrefied heard of biting wolverines franticly drool in the toxic dump you call home. May a festering hoard of South American killer bees have a religious experience upon your heinie.

Further, to dream about big snake in the road can represent this:
May ninty-nine funky, rabid pit-fiends sneeze in the landfill you call home. You gross offspring of a motherless cretin. May a defective platoon of fleas and a noxious hoard of South American killer bees seek a battleground upon your heinie. May forty-two crazed wiener-dogs find your buttocks suddenly delectable.

Alternatively, a dream of big snake in a road may have such symbolism:
You festering ass. May many South American killer bees find your innards suddenly delectable. You lazy offspring of a motherless fuckwad. May a scabrous platoon of disease-carrying weasels gleefully dance in your mother’s shoes.

Also, dreaming about big snakes in road can have more meanings:
May an army of disease-carrying maggots and a slavering Rush Limbaugh seek a battleground upon your heinie. May a truckload of plague-ridden weasels, with the power of Thor’s belch, discharge bodily waste on your best rug. You curdled fondue pot. You stenchy, retarded, assinine, half-baked, fungus for brains.

Finally, also it can mean this: You hirsute dingo. You fetid, shit for brains. You nasty, bat guano for brains. May a sweaty hoard of yaks happily find shelter upon your mother’s grave. So, big snakes in road dream can mean that you’re repulsive offspring of a motherless gekko. May a rotting and rancid group of yaks discharge bodily waste in your shoes. May a biting Rush Limbaugh find your innards suddenly delectable. May the hosts of Hades happily throw a party in the oil refinery you call home. May a truckload of yaks and a gruesome heard of biting weasels seek a battleground upon your heinie. Or big snake in a road dream can mean that you ungrateful, decomposed camel cysts for brains.